Université de Bordeaux
BrainConf: Synaptic Plasticity27-30 September, 2022 - Bordeaux
 

Tom Blanpied

Tom Blanpied, Department of Physiology, University of Maryland School of Medicine, USA

Title

Synaptic nanoorganization that controls receptor activation

Biosketch

Thomas A. Blanpied, PhD, is Professor of Physiology at the University of Maryland School of Medicine. He received his BA in psychobiology from Yale University and a PhD in Neuroscience from the University of Pittsburgh. His postdoctoral work was at Duke University in the Department of Neurobiology, where his focus was the cell biology of synaptic transmission. He moved to Maryland in 2005 and is currently Director of the School of Medicine Core Optical Microscopy Facility. He has taught imaging in a number of contexts, including super-resolution microscopy at the Institute for Neurophotonics in Quebec City, Canada, at Woods Hole, at Cold Spring Harbor Laboratories, and as co-chair of a Society for Neuroscience Short Course on imaging techniques.

The central interests of his lab are to define the molecular nanoarchitecture of glutamatergic synapses, to understand how this intricate protein organization produces synaptic signaling, and to explore how changes to it produce neural plasticity. Exploiting high-resolution live-cell and single-molecule localization microscopy, his work discovered the postsynaptic endocytic zone, demonstrated actin-driven dynamics of protein organization within the postsynaptic density, revealed synaptic scaffold nanodomains where receptors are concentrated, and identified the nanocolumn transsynaptic alignment of receptors with presynaptic release sites.

Website: http://blanpiedlab.org



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